How to take tenofovir
Tenofovir is a widely used antiviral drug, mainly used to treat HIV infection and chronic hepatitis B. In recent years, with the improvement of health awareness, the usage and precautions of tenofovir have become a hot topic. This article will introduce in detail the taking method, dosage, precautions and common questions of tenofovir to help patients use the medication correctly.
1. Basic information about tenofovir

Tenofovir is a nucleotide reverse transcriptase inhibitor that works by inhibiting viral replication. It comes in two common forms: tenofovir disoproxil disoproxil (TDF) and tenofovir alafenamide (TAF). TAF has higher safety and lower side effects than TDF.
| Drug name | Indications | Common dosage forms |
|---|---|---|
| Tenofovir disoproxil disoproxil (TDF) | HIV infection, chronic hepatitis B | 300mg tablet |
| Tenofovir alafenamide (TAF) | HIV infection, chronic hepatitis B | 25mg tablet |
2. How to take tenofovir
How to take tenofovir varies depending on the indication and dosage form. The following are common dosage guidelines:
| Indications | Dosage form | Recommended dosage | Taking time |
|---|---|---|---|
| HIV infection | TDF | 300mg/time, once a day | Can be taken with or without food |
| HIV infection | TAF | 25mg/time, once a day | Take with food |
| chronic hepatitis B | TDF | 300mg/time, once a day | Can be taken with or without food |
| chronic hepatitis B | TAF | 25mg/time, once a day | Take with food |
3. Precautions for tenofovir
1.Kidney function monitoring: Tenofovir may affect renal function, especially TDF. Patients should check their kidney function regularly during medication and adjust the dose if necessary.
2.Bone density monitoring: Long-term use of TDF may lead to a decrease in bone density. It is recommended that high-risk patients undergo regular bone density examinations.
3.drug interactions: Tenofovir may interact with other drugs (such as certain antibiotics and antifungal drugs) and must be used under the guidance of a doctor.
4.Medication for pregnant women: Pregnant women should be cautious when using tenofovir, and should decide whether to take the drug after a doctor's evaluation.
4. Frequently Asked Questions
1.Does tenofovir need to be taken on an empty stomach?
Tenofovir disoproxil (TDF) can be taken on an empty stomach or with food, while tenofovir alafenamide (TAF) is recommended to be taken with food to improve absorption.
2.What should I do if I miss a dose?
If you miss a dose, take it as soon as possible; if it is close to the time of your next dose, skip the missed dose and do not double the dose.
3.What are the side effects of tenofovir?
Common side effects include headache, diarrhea, nausea, etc. Serious side effects such as kidney function damage and decreased bone density require prompt medical treatment.
5. Summary
Tenofovir is an effective antiviral drug, but correct use is critical. Patients should strictly follow medical advice, regularly monitor kidney function and bone density, and pay attention to drug interactions. If you have any questions, you should consult your doctor or pharmacist in time.
Through the presentation of the above structured data, I hope you will have a clearer understanding of how to take tenofovir. Rational use of medication can better control the disease and improve the quality of life.
check the details
check the details